Overdiagnosis and overtreatment of thyroid cancer: A population-based temporal trend study.

ABSTRACT:

Background

The increase in incidence of thyroid cancer during the last decades without concomitant rise in mortality may reflect the growing detection of indolent forms of thyroid cancer, and may have fueled unnecessary thyroidectomies. Our aim was therefore, to compare recent secular trends in surgical intervention rate for thyroid cancer with the incidence and mortality of thyroid cancer to assess overdiagnosis and resulting overtreatment.

Methods

We conducted a population-based temporal trend study in Switzerland from 1998 to 2012. All cases of invasive thyroid cancer, deaths from thyroid cancer, and cancer-related thyroidectomies were analyzed. We calculated changes in age-standardized thyroid cancer incidence rates, stratified by histologic subtype and tumor stage, thyr

SUBMITTER: Jegerlehner S 

PROVIDER: S-EPMC5470703 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature