Bacteriocin Gene-Trait matching across the complete Lactobacillus Pan-genome.

ABSTRACT: Lactobacilli constitute a large genus of Gram-positive lactic acid bacteria which have widespread roles ranging from gut commensals to starters in fermented foods. A combination of in silico and laboratory-based screening allowed us to determine the overall bacteriocin producing potential of representative strains of each species of the genus. The genomes of 175 lactobacilli and 38 associated species were screened for the presence of antimicrobial producing genes and combined with screening for antimicrobial activity against a range of indicators. There also appears to be a link between the strains' environment and bacteriocin production, with those from the animal and human microbiota encoding over twice as many bacteriocins as those from other sources. Five novel bacteriocins were identi

SUBMITTER: Collins FWJ 

PROVIDER: S-EPMC5471241 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature