Characterization of Inpatient Cystic Fibrosis Pulmonary Exacerbations.

ABSTRACT:

Background and objectives

Pulmonary exacerbations lead to significant morbidity and mortality in patients with cystic fibrosis (CF). National consensus guidelines exist, but few studies report current practice in the treatment and monitoring of pulmonary exacerbations. The goal of this study was to characterize consistency and variability in the inpatient management of CF-related pulmonary exacerbations. We focused on the use of guideline-recommended maintenance therapies, antibiotic selection and treatment regimens, use of systemic corticosteroids, and frequency of lung function testing. We hypothesized that significant variability in these treatment practices exists nationally.

Methods

This trial was a retrospective cross-sectional study. It included patients with CF aged

SUBMITTER: Cogen JD 

PROVIDER: S-EPMC5472380 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature