Covalent Capture of Aligned Self-Assembling Nanofibers.

ABSTRACT: A great deal of effort has been invested in the design and characterization of systems which spontaneously assemble into nanofibers. These systems are interesting for their fundamental supramolecular chemistry and have also been shown to be promising materials, particularly for biomedical applications. Multidomain peptides are one such assembler, and in previous work we have demonstrated the reversibility of their assembly under mild and easily controlled conditions, along with their utility for time-controlled drug delivery, protein delivery, cell encapsulation, and cell delivery applications. Additionally, their highly compliant criteria for sequence selection allows them to be modified to incorporate protease susceptibility and biological-recognition motifs for cell adhesion and angioge

SUBMITTER: Li IC 

PROVIDER: S-EPMC5473017 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature