Antibiotic prophylaxis for surgical site infections as a risk factor for infection with Clostridium difficile.

ABSTRACT:

Objective

We aimed to measure the association between 2013 guideline concordant prophylactic antibiotic use prior to surgery and infection with Clostridium difficile.

Design

We conducted a retrospective case-control study by selecting patients who underwent a surgical procedure between January 1, 2012 and December 31, 2013.

Setting

Large urban community hospital.

Patients

Cases and controls were patients age 18+ years who underwent an eligible surgery (i.e., colorectal, neurosurgery, vascular/cardiac/thoracic, hysterectomy, abdominal/pelvic and orthopedic surgical procedures) within six months prior to infection diagnosis. Cases were diagnosed with C. difficile infection while controls were not.

Methods

The primary exposure was receiving (vs. not receivi

SUBMITTER: Balch A 

PROVIDER: S-EPMC5473553 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature