Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b.

ABSTRACT: A novel gene for quinolone resistance was cloned from a transferable plasmid carried by a clinical isolate of Shigella flexneri 2b that was resistant to fluoroquinolones. The plasmid conferred low-level resistance to quinolones on Escherichia coli HB101. The protein encoded by the gene showed 59% amino acid identity with Qnr.

SUBMITTER: Hata M 

PROVIDER: S-EPMC547361 | biostudies-literature | 2005 Feb

REPOSITORIES: biostudies-literature