Genome-wide analysis of codon usage bias in Bovine Coronavirus.

ABSTRACT:

Background

Bovine coronavirus (BCoV) belong to the genus Betacoronavirus of the family Coronaviridae. BCoV are widespread around the world and cause enteric or respiratory infections among cattle, leading to important economic losses to the beef and dairy industry worldwide. To study the relation of codon usage among viruses and their hosts is essential to understand host-pathogen interaction, evasion from host's immune system and evolution.

Methods

We performed a comprehensive analysis of codon usage and composition of BCoV.

Results

The global codon usage among BCoV strains is similar. Significant differences of codon preferences in BCoV genes in relation to codon usage of Bos taurus host genes were found. Most of the highly frequent codons are U-ending. G + C compos

SUBMITTER: Castells M 

PROVIDER: S-EPMC5474002 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature