Influence of Negative Life Events and Widowhood on Risk for Dementia.

ABSTRACT:

Objective

The aim of the current study was to examine the effect of negative life events and widowhood on the incidence of dementia.

Methods

Data were from four Swedish longitudinal cohort studies with a total of nearly 2,000 participants and 8-25 years of follow-up. Seven stressful events were examined for which data were available in all cohorts. Clinical dementia diagnoses were made through medical and psychological examinations. Cox proportional hazards models were used to estimate the association between life events and dementia, adjusting for lifestyle and cardiovascular risk factors.

Results

The experience of one stressful life event was not associated with dementia incidence, but two or more negative life events at baseline predicted higher risk for dementia (

SUBMITTER: Gerritsen L 

PROVIDER: S-EPMC5474139 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature