Disassociating Lung Mechanics and Oxygenation in Pediatric Acute Respiratory Distress Syndrome.

ABSTRACT:

Objectives

Both oxygenation and peak inspiratory pressure are associated with mortality in pediatric acute respiratory distress syndrome. Since oxygenation and respiratory mechanics are linked, it is difficult to identify which variables, pressure or oxygenation, are independently associated with outcome. We aimed to determine whether respiratory mechanics (peak inspiratory pressure, positive end-expiratory pressure, ΔP [PIP minus PEEP], tidal volume, dynamic compliance [Cdyn]) or oxygenation (PaO2/FIO2) was associated with mortality.

Design

Prospective, observational, cohort study.

Setting

University affiliated PICU.

Patients

Mechanically ventilated children with acute respiratory distress syndrome (Berlin).

Interventions

None.

Measurements and main

SUBMITTER: Yehya N 

PROVIDER: S-EPMC5474185 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature