Anti-allergic Hydroxy Fatty Acids from Typhonium blumei Explored through ChemGPS-NP.

ABSTRACT: Increasing prevalence of allergic diseases with an inadequate variety of treatment drives forward search for new alternative drugs. Fatty acids, abundant in nature, are regarded as important bioactive compounds and powerful nutrients playing an important role in lipid homeostasis and inflammation. Phytochemical study on Typhonium blumei Nicolson and Sivadasan (Araceae), a folk anti-cancer and anti-inflammatory medicine, yielded four oxygenated fatty acids, 12R-hydroxyoctadec-9Z,13E-dienoic acid methyl ester (1) and 10R-hydroxyoctadec-8E,12Z-dienoic acid methyl ester (2), 9R-hydroxy-10E-octadecenoic acid methyl ester (3), and 12R^*-hydroxy-10E-octadecenoic acid methyl ester (4)

SUBMITTER: Korinek M 

PROVIDER: S-EPMC5474496 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature