Synovial Sarcoma of the Head and Neck: A Single Institution Review.

ABSTRACT:

Background

The prognosis and clinical characteristics of head and neck synovial sarcomas (HNSS) are unclear. Herein, we present an update using a cohort of patients treated at our institution.

Methods

We performed a retrospective chart review of 44 patients diagnosed with primary HNSS between March 1990 and June 2012. Overall survival (OS) and progression-free survival (PFS) curves were estimated and hazard ratios (HRs) were calculated.

Results

The entire cohort's median PFS was 4.6 years, and 20 of the 44 (45%) patients developed either local or distant recurrence. Tumor size ≥ 5 cm (p = 0.008, HR = 4.69; 95% CI = 1.34-16.38) and a primary presentation in the soft tissues of the neck (p = 0.04, HR = 2.41; 95% CI = 1.003-5.82) were associated with signif

SUBMITTER: Gopalakrishnan V 

PROVIDER: S-EPMC5474548 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature