β-Octabromo- and β-Octakis(trifluoromethyl)isocorroles: New Sterically Constrained Macrocyclic Ligands.

ABSTRACT: Presented herein is a study of the acid-induced demetalation of two sterically hindered copper corroles, Cu β-octabromo-meso-triphenylcorrole (Cu[Br₈TPC]) and β-octakis(trifluoromethyl)-meso-tris(p-methoxyphenyl)corrole (Cu[(CF₃)₈TpOMePC]). Unlike reductive demetalation, which affords the free-base β-octabromocorrole, demetalation of Cu[Br₈TPC] under non- reductive conditions (CHCl₃/H₂SO₄) resulted in moderate yields of free-base 5- and 10-hydroxy isocorroles. The isomeric free bases could be complexed to Co^II and Ni^II, affording stable complexes. Only reductive demetalation was found to work for Cu[(CF₃)₈TpOMePC], affording a highly sa

SUBMITTER: Thomas KE 

PROVIDER: S-EPMC5474668 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature