104. Combined CBSST and Oxytocin for Social Function in People With Schizophrenia

ABSTRACT: Abstract Background: A significant proportion of people with schizophrenia are characterized by impaired ability to socially engage with others, which may reflect social aversion secondary to defeatist beliefs; decreased motivation for social interactions; and/or impairment in the normal reinforcement value of social interactions. Unfortunately, pharmacological interventions have limited benefits for impaired social function, whereas psychosocial interventions provide only partial benefit for this critical aspect of the illness. The development of an effective intervention for functional outcomes remains a central therapeutic challenge. The current study assessed whether the addition of intranasal oxytocin to Cognitive Behavioral Social Skills Training (CBSST) improved social function. Met

SUBMITTER: Buchanan R 

PROVIDER: S-EPMC5475600 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature