Influence of pathologist experience on positive surgical margins following radical prostatectomy.

ABSTRACT:

Background

A positive surgical margin (PSM) following radical prostatectomy (RP) for prostate cancer is associated with increased risk of biochemical recurrence. We sought to examine whether the pathologist is an independent predictor of PSMs.

Methods

We performed a retrospective review of 3,557 men who underwent RP for localized prostate cancer at our institution from 2003 to 2015. We evaluated 29 separate pathologists. Univariate and multivariable logistic regression were used to test variables previously shown to influence PSM rates.

Results

Overall rate of PSM was 18.9%. Compared with patients without PSM, patients with PSM had higher body mass index (mean: 28.8 vs. 28.3), Gleason score≥7 (84% vs. 66%), extracapsular extension (51% vs. 20%), and median prostate-sp

SUBMITTER: Tallman JE 

PROVIDER: S-EPMC5476525 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature