Early body composition, but not body mass, is associated with future accelerated decline in muscle quality.

ABSTRACT:

Background

Muscle quality (MQ) or strength-to-mass ratio declines with aging, but the rate of MQ change with aging is highly heterogeneous across individuals. The identification of risk factors for accelerated MQ decline may offer clues to identity the underpinning physiological mechanisms and indicate targets for prevention and treatment. Using data from the Baltimore Longitudinal Study of Aging, we tested whether measures of body mass and body composition are associated with differential rates of changes in MQ with aging.

Methods

Participants included 511 men and women, aged 50 years or older, followed for an average of 4 years (range: 1-8). MQ was operationalized as ratio between knee-extension isokinetic strength and CT-thigh muscle cross-sectional area. Predictors inclu

SUBMITTER: Fabbri E 

PROVIDER: S-EPMC5476863 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature