Chiral hemicucurbit[8]uril as an anion receptor: selectivity to size, shape and charge distribution.

ABSTRACT: A novel eight-membered macrocycle of the hemicucurbit[n]uril family, chiral (all-R)-cyclohexanohemicucurbit[8]uril (cycHC[8]) ‡The name cyclohexylhemicucurbituril, previously used for these macrocycles, is changed in accordance with the IUPAC nomenclature for fused cycles, as the cyclohexane substituents are fused with the parent hemicucurbituril. binds anions in a purely protic solvent with remarkable selectivity. The cycHC[8] portals open and close to fully encapsulate anions in a 1 : 1 ratio, resembling a molecular Pac-Man™. Comprehensive gas, solution and solid phase studies prove that the binding is governed by the size, shape and charge distribution of the bound anion. Gas phase studies show an order of SbF₆^- ≈ PF₆^-

SUBMITTER: Kaabel S 

PROVIDER: S-EPMC5477839 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature