Central Nervous System Medication Burden and Serious Falls in Older Nursing Home Residents.

ABSTRACT:

Objectives

To examine the association between CNS medication burden and serious falls in those with a recent fall history.

Design

Nested-case control study; cases matched to four controls by age, gender, and date.

Setting

US nursing homes.

Participants

5,556 residents age ≥65 with a recent fall history admitted to a nursing home between 1/1-9/30/2010 and followed until discharge, death, or December 31, 2010.

Measurements

Outcome was serious falls as per Medicare Part A and B ICD/CPT codes. CNS burden, from Medicare Part D data, was calculated by dividing the daily dose of each CNS agent (i.e., specific antidepressants, antiepileptic, antipsychotic, benzodiazepine and opioid receptor agonists) received during the 6 days prior to the index (outcome) date b

SUBMITTER: Hanlon JT 

PROVIDER: S-EPMC5478454 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature