OrthoReD: a rapid and accurate orthology prediction tool with low computational requirement.

ABSTRACT:

Background

Identifying orthologous genes is an initial step required for phylogenetics, and it is also a common strategy employed in functional genetics to find candidates for functionally equivalent genes across multiple species. At the same time, in silico orthology prediction tools often require large computational resources only available on computing clusters. Here we present OrthoReD, an open-source orthology prediction tool with accuracy comparable to published tools that requires only a desktop computer. The low computational resource requirement of OrthoReD is achieved by repeating orthology searches on one gene of interest at a time, thereby generating a reduced dataset to limit the scope of orthology search for each gene of interest.

Results

The output of OrthoReD

SUBMITTER: Battenberg K 

PROVIDER: S-EPMC5479036 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature