Genetic characteristic of class 1 integrons in proteus mirabilis isolates from urine samples.

ABSTRACT:

Background

Proteus mirabilis is an opportunistic pathogen, commonly associated with complicated urinary tract infections (UTIs). UTIs caused by multidrug-resistant Proteus mirabilis have increased worldwide. Multidrug-resistance of Gram-negative enteric bacteria is usually associated with class 1 integrons.

Purposes

To investigate the prevalence and characterize gene cassettes of class 1 integrons in multidrug-resistant P. mirabilis Methods: From 2006 to 2008, 314 P. mirabilis isolates from urine were collected from a regional teaching hospital. Antimicrobial resistance of the isolates was determined by disk diffusion methods. The phenotypic confirmatory test of extended-spectrum β-lactamase (ESBL) production was performed as described in the Clinical and Laboratory Standard

SUBMITTER: Chen CM 

PROVIDER: S-EPMC5479437 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature