Metabolically-healthy obesity is associated with higher prevalence of colorectal adenoma.

ABSTRACT:

Background

The risk of colorectal adenoma (CRA), an important precursor of colorectal cancer, is largely unknown among obese individuals without obesity-related metabolic abnormalities, a condition described as metabolically-healthy obese (MHO). The aim of this study was to examine the association among metabolic status, the different categories of body mass index (BMI), and CRA in a large cohort of adults.

Methods

We analyzed the association among metabolic status, BMI categories and CRA in asymptomatic adults who underwent a first-time colonoscopy as part of the comprehensive health check-up program at the Health Promotion Center of Samsung Medical Center, from January 2005 to December 2012. Being metabolically healthy was defined as lacking any metabolic syndrome componen

SUBMITTER: Sinn DH 

PROVIDER: S-EPMC5479542 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature