Aortic sinus flow stasis likely in valve-in-valve transcatheter aortic valve implantation.

ABSTRACT:

Objective

Valve-in-valve procedures using transcatheter aortic valves are increasingly performed to treat degenerated bioprosthetic surgical aortic valves because they are less invasive than redo aortic valve replacement. The objective of this study is to quantify the changes in aortic sinus blood flow dynamics before and after a valve-in-valve procedure to gain insight into mechanisms for clinical and subclinical thrombosis of leaflets.

Methods

A detailed description of the sinus hemodynamics for valve-in-valve implantation was performed in vitro. A Medtronic Hancock II (Medtronic Inc, Minneapolis, Minn) porcine bioprosthesis was modeled as a surgical aortic valve, and Medtronic CoreValve and Edwards Sapien (Edwards Lifesciences, Irvine, Calif) valves were used as the trans

SUBMITTER: Hatoum H 

PROVIDER: S-EPMC5479725 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature