Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men.

ABSTRACT: Introduction/Purpose: A number of studies have investigated the effect of training with a moderate exercise dose (3-6 h/weekly) on the inflammatory profile in blood, and the data are inconsistent. Cross-sectional studies indicate a positive effect of physical activity level on inflammation levels and risk of metabolic disease. However, it is not clear whether this may be dose dependent and if very prolonged repeated exercise therefore may be beneficial for low-grade inflammation. Based on this we studied how excessive repeated prolonged exercise influenced low-grade inflammation and adipose tissue anti-inflammatory macrophage content in six older male recreationally trained cyclists. Low-grade inflammation and adipose tissue macrophage content were investigated in six older trained

SUBMITTER: Sahl RE 

PROVIDER: S-EPMC5479888 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature