Association of Slow Gait Speed With Trajectories of Worsening Depressive Symptoms in Knee Osteoarthritis: An Observational Study.

ABSTRACT:

Objective

To investigate the association of slow gait speed, defined as walking slower than is necessary for the community, with trajectories of depressive symptoms over 7 years among people with or at high risk of knee OA.

Methods

Using data from the Osteoarthritis Initiative, we described trajectories of depressive symptoms measured annually with the Center for Epidemiologic Studies Depression Scale. We categorized speed during a 20-meter walk of <1.2 meters/second as slow gait speed. We used a group-based method to agnostically identify homogeneous clusters of depressive symptom trajectories. We then examined the association of slow gait speed with depressive symptom trajectories, using multinomial logistic regression adjusted for potential confounders.

Results

Fro

SUBMITTER: White DK 

PROVIDER: S-EPMC5480310 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature