Impact of folate intake on prostate cancer recurrence following definitive therapy: data from CaPSURE™.

ABSTRACT:

Purpose

A randomized, placebo controlled clinical trial of folic acid supplementation for the chemoprevention of colorectal adenoma revealed an increased incidence of prostate cancer in the treatment group. Limited data exist on postdiagnostic folate/folic acid intake and the risk of prostate cancer progression. We prospectively examined the association between postdiagnostic folate consumption and the risk of prostate cancer recurrence after radical prostatectomy, external beam radiation therapy and brachytherapy.

Materials and methods

This study was done in 1,153 men treated with radical prostatectomy, external beam radiation therapy and brachytherapy who had clinical stage T1-T2c prostate adenocarcinoma and participated in the CaPSURE Diet and Lifestyle substudy by comple

SUBMITTER: Tomaszewski JJ 

PROVIDER: S-EPMC5480381 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature