Relationships among Bone Quality, Implant Osseointegration, and Wnt Signaling.

ABSTRACT: A variety of clinical classification schemes have been proposed as a means to identify sites in the oral cavity where implant osseointegration is likely to be successful. Most schemes are based on structural characteristics of the bone, for example, the relative proportion of densely compact, homogenous (type I) bone versus more trabeculated, cancellous (type III) bone. None of these schemes, however, consider potential biological characteristics of the bone. Here, we employed multiscale analyses to identify and characterize type I and type III bones in murine jaws. We then combined these analytical tools with in vivo models of osteotomy healing and implant osseointegration to determine if one type of bone healed faster and supported osseointegration better than another. Collectively, thes

SUBMITTER: Li J 

PROVIDER: S-EPMC5480808 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature