Burden and impact of Plasmodium vivax in pregnancy: A multi-centre prospective observational study.

ABSTRACT:

Background

Despite that over 90 million pregnancies are at risk of Plasmodium vivax infection annually, little is known about the epidemiology and impact of the infection in pregnancy.

Methodology and principal findings

We undertook a health facility-based prospective observational study in pregnant women from Guatemala (GT), Colombia (CO), Brazil (BR), India (IN) and Papua New Guinea PNG). Malaria and anemia were determined during pregnancy and fetal outcomes assessed at delivery. A total of 9388 women were enrolled at antennal care (ANC), of whom 53% (4957) were followed until delivery. Prevalence of P. vivax monoinfection in maternal blood at delivery was 0.4% (20/4461) by microscopy [GT 0.1%, CO 0.5%, BR 0.1%, IN 0.2%, PNG 1.2%] and 7% (104/1488) by PCR. P. falciparum mo

SUBMITTER: Bardaji A 

PROVIDER: S-EPMC5481034 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature