Bone Mineral Density Response from Teriparatide in Patients with Osteoporosis.

ABSTRACT:

Background

A review of data from large clinical trials reported more than 90% of subjects significantly improved their bone mineral density (BMD) at the lumbar spine (LS) with teriparatide (TPTD) (bone 39:1268-1275, 1). However, our clinical experience suggests that many patients may be non-responders, raising questions as to the true efficacy of TPTD in improving BMD in osteoporotic patients.

Questions/purposes

The purpose of the study is to determine the rate of improvement in BMD following 18-24 months of teriparatide (TPTD) in patients with osteoporosis within an orthopedic hospital setting.

Methods

This is a retrospective chart review of patients with osteoporosis who completed 18-24 months of TPTD therapy. The primary endpoint was the change in BMD at lumbar spi

SUBMITTER: Kim SY 

PROVIDER: S-EPMC5481259 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature