Total Knee Arthroplasty for Knee Osteoarthritis: Support for a Foregone Conclusion?

ABSTRACT: Total knee arthroplasty (TKA) is generally accepted as the definitive treatment for advanced knee arthritis after patients fail nonoperative treatments; however, the safety and efficacy of TKA compared to continued nonoperative treatment has never been proven in high-quality, randomized controlled trials. Recently, a 2015 Danish study published a 12-month follow-up on a cohort of patients randomized to either a TKA or continued nonsurgical management for advanced knee osteoarthritis (OA). The authors reported significantly greater improvement in the TKA group in functional outcome scores such as the overall Knee Injury and Osteoarthritis Outcome Score (KOOS₄ score), the KOOS subscales, EQ-5D descriptive index, and timed get up-and-go and 20-m walk tests; however, patients in the

SUBMITTER: Steinhaus ME 

PROVIDER: S-EPMC5481268 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature