Predictors of Waitlist Mortality in Portopulmonary Hypertension.

ABSTRACT:

Background

The current Organ Procurement Transplantation Network policy grants Model for End-Stage Liver Disease (MELD) exception points to patients with portopulmonary hypertension (POPH), but potentially important factors, such as severity of liver disease and pulmonary hypertension, are not included in the exception score, and may affect survival. The purpose of this study was to identify significant predictors of waitlist mortality in patients with POPH.

Methods

We performed a retrospective cohort study of patients in the Organ Procurement and Transplantation Network database with hemodynamics consistent with POPH (defined as mean pulmonary arterial pressure >25 mm Hg and pulmonary vascular resistance [PVR] ≥240 dynes·s·cm) who were approved for a POPH MELD exception bet

SUBMITTER: DuBrock HM 

PROVIDER: S-EPMC5481480 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature