Exploring bacterial interspecific interactions for discovery of novel antimicrobial compounds.

ABSTRACT: Recent studies indicated that the production of secondary metabolites by soil bacteria can be triggered by interspecific interactions. However, little is known to date about interspecific interactions between Gram-positive and Gram-negative bacteria. In this study, we aimed to understand how the interspecific interaction between the Gram-positive Paenibacillus sp. AD87 and the Gram-negative Burkholderia sp. AD24 affects the fitness, gene expression and the production of soluble and volatile secondary metabolites of both bacteria. To obtain better insight into this interaction, transcriptome and metabolome analyses were performed. Our results revealed that the interaction between the two bacteria affected their fitness, gene expression and the production of secondary metabolites. During int

SUBMITTER: Tyc O 

PROVIDER: S-EPMC5481530 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature