Regular Exercise, Quality of Life, and Mobility in Parkinson's Disease: A Longitudinal Analysis of National Parkinson Foundation Quality Improvement Initiative Data.

ABSTRACT:

Background

Research-based exercise interventions improve health-related quality of life (HRQL) and mobility in people with Parkinson's disease (PD).

Objective

To examine whether exercise habits were associated with changes in HRQL and mobility over two years.

Methods

We identified a cohort of National Parkinson Foundation Quality Improvement Initiative (NPF-QII) participants with three visits. HRQL and mobility were measured with the Parkinson's Disease Questionnaire (PDQ-39) and Timed Up and Go (TUG). We compared self-reported regular exercisers (≥2.5 hours/week) with people who did not exercise 2.5 hours/week. Then we quantified changes in HRQL and mobility associated with 30-minute increases in exercise, across PD severity, using mixed effects regression models.

SUBMITTER: Rafferty MR 

PROVIDER: S-EPMC5482526 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature