Association between KCNE1 G38S gene polymorphism and risk of atrial fibrillation: A PRISMA-compliant meta-analysis.

ABSTRACT:

Background

Previous case-control studies on association between KCNE1 G38S polymorphism and risk of atrial fibrillation (AF) have been published but because of the conflicting results and small sample size of individual studies, the consolidated result is still controversial.

Objectives

The aim of this study was to explore the relationship between KCNE1 G38S polymorphism and risk of AF.

Methods

We performed a comprehensive literature search on PubMed, Embase, OVID, Web of Science, Wan Fang, and CNKI databases up to March 10, 2017 in English and Chinese languages. Two of the authors individually extracted study data and assessed the study quality using Newcastle-Ottawa scale. Odds ratios (ORs) and 95% confidence intervals (CIs) were combined in different genetic models

SUBMITTER: Jiang YF 

PROVIDER: S-EPMC5484235 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature