Intravoxel incoherent motion modeling in the kidneys: Comparison of mono-, bi-, and triexponential fit.

ABSTRACT:

Purpose

To evaluate if a three-component model correctly describes the diffusion signal in the kidney and whether it can provide complementary anatomical or physiological information about the underlying tissue.

Materials and methods

Ten healthy volunteers were examined at 3T, with T₂ -weighted imaging, diffusion tensor imaging (DTI), and intravoxel incoherent motion (IVIM). Diffusion tensor parameters (mean diffusivity [MD] and fractional anisotropy [FA]) were obtained by iterative weighted linear least squares fitting of the DTI data and mono-, bi-, and triexponential fit parameters (D₁ , D₂ , D₃ , f_fast2 , f_fast3 , and f_interm ) using a nonlinear fit of the IVIM data. Average parameters were calc

SUBMITTER: van Baalen S 

PROVIDER: S-EPMC5484284 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature