Cannabis use and symptom severity in individuals at ultra high risk for psychosis: a meta-analysis.

ABSTRACT:

Objective

We aimed to assess whether individuals at ultra high risk (UHR) for psychosis have higher rates of cannabis use and cannabis use disorders (CUDs) than non-UHR individuals and determine whether UHR cannabis users have more severe psychotic experiences than non-users.

Method

We conducted a meta-analysis of studies reporting cannabis use in the UHR group and/or positive or negative symptoms among UHR cannabis users and non-users. Logit event rates were calculated for cannabis use, in addition to odds ratios to assess the difference between UHR and controls. Severity of clinical symptoms in UHR cannabis users and non-users was compared using Hedges' g.

Results

Thirty unique studies were included (UHR n = 4205, controls n = 667) containing data from cross-section

SUBMITTER: Carney R 

PROVIDER: S-EPMC5484316 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature