Pathways from maternal depression to young adult offspring depression: an exploratory longitudinal mediation analysis.

ABSTRACT: Maternal depression in the peri-natal period is associated with increased risk for young adult depression in offspring. This study explored mediation of these links via trajectories of child conduct and emotional problems (Strengths and Difficulties Questionnaire) from ages 4-16 years old in data from the Avon Longitudinal Study of Parents and Children cohort (n = 13373). Through gender-specific structural equation models, a composite measure of exposure to early maternal depression (Edinburgh Postnatal Depression Scale), predicted young adult depression at age 18 (Revised Clinical Interview Schedule - distal outcome). Mediational effects were then estimated by testing which parts of joint piecewise latent trajectory models for child/adolescent conduct and emotional problems were associate

SUBMITTER: Koukounari A 

PROVIDER: S-EPMC5484332 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature