High Glycated Albumin and Mortality in Persons with Diabetes Mellitus on Hemodialysis.

ABSTRACT:

Background

Monitoring of glycemic control with hemoglobin A_1c (A1c) in hemodialysis patients may be compromised by anemia and erythropoietin therapy. Glycated albumin (GA) is an alternative measure of glycemic control but is not commonly used because of insufficient evidence of association to clinical outcomes. We tested whether GA measurements were associated with mortality in hemodialysis patients with diabetes mellitus.

Methods

The German Diabetes and Dialysis Study (4D) investigated effects of atorvastatin on survival in 1255 patients with diabetes mellitus receiving hemodialysis. We measured GA during months 0, 6, and 12. Cox proportional hazards analysis was used to measure associations between GA and A1c and all-cause mortality.

Results

Patients with

SUBMITTER: Chen CW 

PROVIDER: S-EPMC5484581 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature