Clinical and Fecal Microbial Changes With Diet Therapy in Active Inflammatory Bowel Disease.

ABSTRACT:

Goal

To determine the effect of the specific carbohydrate diet (SCD) on active inflammatory bowel disease (IBD).

Background

IBD is a chronic idiopathic inflammatory intestinal disorder associated with fecal dysbiosis. Diet is a potential therapeutic option for IBD based on the hypothesis that changing the fecal dysbiosis could decrease intestinal inflammation.

Study

Pediatric patients with mild to moderate IBD defined by pediatric Crohn's disease activity index (PCDAI 10-45) or pediatric ulcerative colitis activity index (PUCAI 10-65) were enrolled into a prospective study of the SCD. Patients started SCD with follow-up evaluations at 2, 4, 8, and 12 weeks. PCDAI/PUCAI, laboratory studies were assessed.

Results

Twelve patients, ages 10 to 17 years, were enrolle

SUBMITTER: Suskind DL 

PROVIDER: S-EPMC5484760 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature