Global translational reprogramming is a fundamental layer of immune regulation in plants.

ABSTRACT: In the absence of specialized immune cells, the need for plants to reprogram transcription to transition from growth-related activities to defence is well understood. However, little is known about translational changes that occur during immune induction. Using ribosome footprinting, here we perform global translatome profiling on Arabidopsis exposed to the microbe-associated molecular pattern elf18. We find that during this pattern-triggered immunity, translation is tightly regulated and poorly correlated with transcription. Identification of genes with altered translational efficiency leads to the discovery of novel regulators of this immune response. Further investigation of these genes shows that messenger RNA sequence features are major determinants of the observed translational effic

SUBMITTER: Xu G 

PROVIDER: S-EPMC5485861 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature