Identification of Proteases and Protease Inhibitors in Allergenic and Non-Allergenic Pollen.

ABSTRACT: Pollen is one of the most common causes of allergy worldwide, making the study of their molecular composition crucial for the advancement of allergy research. Despite substantial efforts in this field, it is not yet clear why some plant pollens strongly provoke allergies while others do not. However, proteases and protease inhibitors from allergen sources are known to play an important role in the development of pollen allergies. In this study, we aim to uncover differences in the transcriptional pattern of proteases and protease inhibitors in Betula verrucosa and Pinus sylvestris pollen as models for high and low allergenic potential, respectively. We applied RNA sequencing to Betula verrucosa and Pinus sylvestris pollen. After de-novo assembly we derived gener

SUBMITTER: Hollbacher B 

PROVIDER: S-EPMC5486022 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature