Improvement of atropine on esophagogastric junction observation during sedative esophagogastroduodenoscopy.

ABSTRACT:

Background and study aims

Although sedation esophagogastroduodenoscopy (EGD) is now widely used, previous research has reported that sedation during EGD exhibits a negative effect on esophagogastric junction (EGJ) exposure. Atropine might improve EGJ exposure, as noted in clinical practice. The aim of this study was to examine whether sedation had a negative effect on EGJ observation in the Chinese population, and whether atropine had some ability to act as an antidote to this unexpected secondary effect of sedation.

Patients and methods

In this cross-sectional study, subjects were divided into the following three groups according to the methods of EGD examination: the non-sedation group, the propofol-fentanyl combined sedation group and the combined sedation with atropine a

SUBMITTER: Chen Z 

PROVIDER: S-EPMC5487030 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature