Evaluation of the association between the TAS1R2 and TAS1R3 variants and food intake and nutritional status in children.

ABSTRACT: Taste perception plays a key role in determining individual food preferences and dietary habits and may influence nutritional status. This study aimed to investigate the association of TAS1R2 (Ile191Val - rs35874116) and TAS1R3 (-1266 C/T - rs35744813) variants with food intake and nutritional status in children followed from birth until 7.7 years old. The nutritional status and food intake data of 312 children were collected at three developmental stages (1, 3.9 and 7.7 years old). DNA was extracted from blood samples and the polymorphisms were analyzed by real-time polymerase chain reactions (qPCR) using hydrolysis probes as the detection method. Food intake and nutritional status were compared among individuals with different single nucleotide polymorphism (SNP) genotypes. At 3.9 years

SUBMITTER: Melo SV 

PROVIDER: S-EPMC5488460 | biostudies-literature | 2017 Apr-Jun

REPOSITORIES: biostudies-literature