Hemodynamic numerical simulations of the disturbance due to intracoronary flow measurements by a Doppler guide wire.

ABSTRACT:

Background

Since hemodynamics plays a key role in the development and evolution of cardiovascular pathologies, physician's decision must be based on proper monitoring of relevant physiological flow quantities.

Methods

A numerical analysis of the error introduced by an intravascular Doppler guide wire on the peak velocity measurements has been carried out. The effect of probe misalignment (±10°) with respect to the vessel axis was investigated. Numerical simulations were performed on a realistic 3D geometry, reconstructed from coronary angiography images. Furthermore, instead of using Poiseuille or Womersley approximations, the unsteady pulsatile inlet boundary condition has been calculated from experimental peak-velocity measurements inside the vessel through a new approach

SUBMITTER: Chodzynski KJ 

PROVIDER: S-EPMC5490210 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature