Cerebrovascular fibromuscular dysplasia: The MGH cohort and literature review.

ABSTRACT:

Background

Fibromuscular dysplasia (FMD) is a rare noninflammatory, nonatherosclerotic arteriopathy of medium-sized arteries affecting up to 7% of the population. The disease can affect any artery but commonly affects renal, extracranial carotid, and vertebral arteries. The epidemiology and natural course of cerebrovascular FMD is unknown and requires further investigation.

Methods

We present demographic and outcomes data on a case series of 81 patients with cerebrovascular FMD from Massachusetts General Hospital presenting between 2011 and 2015 followed by a review of the peer-reviewed literature.

Results

Patients were a median age of 53 years (±12 SD) and the majority were women. Approximately 50% had a history of tobacco use and more than two-thirds had hypertensio

SUBMITTER: Harriott AM 

PROVIDER: S-EPMC5490381 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature