Ontology highlight
ABSTRACT:
SUBMITTER: Chung AW
PROVIDER: S-EPMC5490491 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Cell 20151101 4
While antibody titers and neutralization are considered the gold standard for the selection of successful vaccines, these parameters are often inadequate predictors of protective immunity. As antibodies mediate an array of extra-neutralizing Fc functions, when neutralization fails to predict protection, investigating Fc-mediated activity may help identify immunological correlates and mechanism(s) of humoral protection. Here, we used an integrative approach termed Systems Serology to analyze rela ...[more]