Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial.

ABSTRACT:

Trial design

Trachoma is targeted for global elimination. Infection rates with Chlamydia trachomatis are higher in new arrivals to a community and in travelers who leave for extended periods, suggesting they are sources of re-infection. This community-randomized, clinical trial was designed to determine if a surveillance program that targeted newcomers and travelers, identified weekly, would result in more communities achieving levels of infection of ≤1%.

Methods

52 communities were randomly allocated 1:1 to the control (annual MDA alone if warranted) or intervention arm (annual MDA if warranted, plus a surveillance program to identify and treat newcomers and travelers). In each community, surveys were completed every six months on a random sample of 100 children ages 1-9 ye

SUBMITTER: West SK 

PROVIDER: S-EPMC5490954 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature