Integrons and transposons on the Salmonella enterica serovar typhimurium virulence plasmid.

ABSTRACT: A virulence plasmid was identified in a multidrug-resistant Salmonella enterica serotype Typhimurium strain carrying the spvC, rck, and pefA virulence genes and two class 1 integrons linked to the Tn21 and Tn1696 transposons. A novel trimethoprim resistance gene, designated dfrA23, was also identified within the integron region. The association of multidrug resistance and virulence determinants represents an interesting example of virulence plasmid evolution.

SUBMITTER: Villa L 

PROVIDER: S-EPMC549245 | biostudies-literature | 2005 Mar

REPOSITORIES: biostudies-literature