Effects of Bifidobacterium animalis subsp. lactis BB-12^® on the lipid/lipoprotein profile and short chain fatty acids in healthy young adults: a randomized controlled trial.

ABSTRACT:

Background

Some probiotics have hypocholesterolemic effects in animal studies, which are mediated, in part, by increases in fecal short chain fatty acids (SCFAs). Clinical trials of probiotics on lipids/lipoproteins are inconsistent.

Objective

We examined the effects of Bifidobacterium animalis subsp. lactis BB-12^® (BB-12^®) (3.16 × 10⁹ CFUs/day) on lipids and lipoproteins and fecal excretion of SCFAs in healthy adults.

Methods

In a randomized, partially blinded, 4-period, crossover study, 30 adults (11 men, 19 women) aged 18-40 years were randomly assigned to: 1) yogurt smoothie with no BB-12^® (YS), 2) yogurt smoothie with BB-12^® added pre-fermentation (PRE), 3) yogurt smoothie with BB-12^® added post-fe

SUBMITTER: Lee Y 

PROVIDER: S-EPMC5492721 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature