Localization of Unknown Primary Site with ⁶⁸Ga-DOTATOC PET/CT in Patients with Metastatic Neuroendocrine Tumor.

ABSTRACT: Localization of the site of the unknown primary tumor is critical for surgical treatment of patients presenting with neuroendocrine tumor (NET) with metastases. Methods: Forty patients with metastatic NET and unknown primary site underwent ⁶⁸Ga-DOTATOC PET/CT in a single-site prospective study. The ⁶⁸Ga-DOTATOC PET/CT was considered true-positive if the positive primary site was confirmed by histology or follow-up imaging. The scan was considered false-positive if no primary lesion was found corresponding to the ⁶⁸Ga-DOTATOC-positive site. All negative scans for primary tumor were considered false-negative. A scan was classified unconfirmed if ⁶⁸Ga-DOTATOC PET/CT suggested a primary, however, no histology was obtained and imaging follow-up

SUBMITTER: Menda Y 

PROVIDER: S-EPMC5493006 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature