Automatic high-resolution infarct detection using volumetric multiphase dual-energy CT.

ABSTRACT:

Objectives

Late contrast enhancement CT (LCE-CT) visualizes the presence of myocardial infarcts. Differentiation of the contrast-enhanced infarct from blood pool is challenging. We developed a novel method using data from first pass CT angiography (CTA) imaging to enable automatic infarct detection.

Materials and methods

A canine model of myocardial infarction was produced in 11 animals. Two months later, first pass CTA (90 kVp) and LCE-CT (dual energy 90 kVp/150 kVp tin filtered) were performed. Late gadolinium enhancement MRI was used as reference standard. The CTA and LCE-CT were co-registered using a fully automatic non-rigid method based on curved B-splines. The method allowed for limited elastic deformation and the considerable differences in attenuation between first-

SUBMITTER: Sandfort V 

PROVIDER: S-EPMC5493020 | biostudies-literature | 2017 Jul - Aug

REPOSITORIES: biostudies-literature