The Utility of Repeat Culture in Fungal Corneal Ulcer Management: A Secondary Analysis of the MUTT-I Randomized Clinical Trial.

ABSTRACT:

Purpose

To determine whether patients who had a positive repeated culture was predictive of worse clinical outcome than those who achieved microbiological cure at 6 days in the Mycotic Ulcer Treatment Trial I (MUTT-I).

Design

Secondary analysis from a multicenter, double-masked, randomized clinical trial.

Methods

setting: Multiple hospital sites of the Aravind Eye Care System, India.

Study population

Patients with culture-positive filamentous fungal ulcers and visual acuity of 20/40 to 20/400 reexamined 6 days after initiation of treatment.

Intervention

Corneal scraping and cultures were obtained from study participants at day 6 after enrollment.

Main outcome measures

We assessed 3-month best spectacle-corrected visual acuity (BSCVA), 3-month infi

SUBMITTER: Ray KJ 

PROVIDER: S-EPMC5493314 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature